Name: Antilymphocyte Globulin (ALG)
Class: Immunosuppressant
Mechanism: Polyclonal antibody to human lymphocytes (not selective to CD3) ® destruction and inactivation of lymphocytes.
Absorption:
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: Chills, fever, thrombocytopenia, erythema, pruritis, hypersensitivity rxns, anti-ALG antibody production (\ only given for 1-2 weeks).
Utility: Prevent or reverse acute allograft rejection.
Special Features: