Name: Misoprostol (Cytotec)
Class: Prostaglandin Analogue (PGE1)
Mechanism: Stim. mucus and bicarbonate secretion, mucosal blood flow, cell turnover. Inhib. acid secretion.
Absorption:
Dist.:
Metabolism.:
Excretion, t½: Longer t½ than natural prostaglandins.
Toxicity/S.E.s: intest. secretion ® diarrhea. Nausea. Uterine contractions. \ c/i during pregnancy.
Utility: PUD, prevention of NSAID injury.
Special Features: