Name: Dipyridamole (Persantine)
Class: Antithrombotic Agent (Antiplatelet Agent)
Mechanism: Inhib. PDE in platelets ® cAMP ® inhib. of platelet activation.
Absorption:
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Metabolism.:
Excretion, t½:
Toxicity/S.E.s:
Utility: Prevention of systemic embolism in pts. w/prosthetic heart valves. Admin. in combination w/warfarin.
Special Features: When used alone, ineffective for Rx of cerebral or CV thrombotic events. Not proven to be of additional benefit when admin. w/aspirin. Antithrombotic use is primarily for arterial thromboses.