Name: Bisacodyl Tannex (Clysodrast)
Class: Laxative (Contact Cathartic) (Diphenylmethane Cathartic)
Mechanism: Act on colon ® peristalsis.
Absorption: Enema.
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: Fluid and electrolyte depletion, abdominal cramping, Metabolismolic acidosis or alkalosis, hypocalcemia, tetany. Tannic acid in large amounts is hepatotoxic. Use caution w/multiple enemas. Don’t use in pts. w/colonic ulcers or in kids < style=""> Don’t use > 7.5 g at a time or > 10 g over 72 hr.
Utility: Preparation of colon for surgery or X-ray.
Special Features: Indiv. effective doses vary 4-8x. Acid/base indicator ® pink/red urine.