Name: Psyllium (Metamucil)
Class: Laxative (Bulk-Forming Agent)
Mechanism: Absorbs and retains water, increases fecal volume ® rate of transit.
Absorption: Not absorbed.
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: Can bind other drugs ® reduced absorption. Admin. > 1 hr before or after other medication.
Utility: Laxative. Esp. useful in pts. w/alternating constipation and diarrhea (e.g., irritable bowel synd) ® ¯ fluidity of liquid stools and softening of hard stools. Also useful for pts who are on low residue diets; are postpartum; are elderly; or have diverticular disease, spastic colon, or hemorrhoids.
Special Features: Inert, hydrophilic. Introduce gradually to avoid GI impaction. Gentle agent. Requires 1/2-3 days for effect.