Name: Paregoric
Class: Opioid (Antidiarrheal)
Mechanism: Preparation of oral morphine, anise oil, benzoic acid, camphor, diluted alcohol, and glycerin. Increased gastric tone ® delayed gastric emptying. tone and ¯ propulsive peristaltic waves in large intest. ® ¯ gut motility. Effects due to inhib. of ACh release by neurons in the intest. wall. Naloxone sensitive.
Absorption: Oral
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s:
Utility: Antidiarrheal.
Special Features: