Name: Diazoxide (Hyperstat I.V.)
Class: CHF Rx (Vasodilator) (Antihypertensive)
Mechanism: Direct arteriolar vasodilation ® ¯ TPR ® reflex in HR & CO.
Absorption: IV.
Dist.:
Metabolism.:
Excretion, t½: Long duration of action.
Toxicity/S.E.s: Severe tachycardia, prolonged hypotension (possibly resulting in stroke or MI).
Utility: Treat hypertensive emergencies, hypertensive encephalopathy, and eclampsia.
Special Features: