Name: Norgestrel (Ovrette)
Class: Oral Contraceptive (Mini-Pill) (Low-Dose Progestin)
Mechanism: Doesn’t always inhibit ovulation. Produces changes in cervical mucus ® block of sperm penetration.
Absorption: Oral
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: High incidence of abnormal bleeding. Headaches, depression.
Utility: Contraception, esp. in patients c/i for estrogen therapy.
Special Features: Less effective than estrogen-progestin combination pills. None of the cardiovascular toxicity of the combination pill.