Name: Diethylstilbestrol (DES)
Class: Teratogen With Delayed Developmental Defects
Mechanism:
Absorption:
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: Female fetuses exposed to diethylstilbestrol are at increased risk for vaginal adenosis and clear cell vaginal adenocarcinoma after puberty. Risk present in all trimesters.
Utility:
Special Features: Previously commonly used to treat pregnant women who were threatening spontaneous abortion.