Name: Cocaine
Class: CNS Stimulant (Indirect Sympathomimetic Agent)
Mechanism: Inhib. reuptake of catecholamines (DA, NE, 5HT) ® prolonged action. Local anesthetic properties. Also elevation of mood, euphoria, self-esteem, energy, ¯ sense of fatigue. Moderate dose ® HR, BP.
Absorption:
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: Fever, nausea, vomiting, confusion, headache, seizures.
Utility: Used in ENT surgery to produce local anesthesia, hemostasis, vasoconstriction.
Special Features: