Name: Phenylephrine
Class: a1 Agonist (OTC)
Mech.: Stim. a1. Some b at doses. Marked vasoconstriction ® systolic and diastolic pressures and marked reflex bradycardia.
Absorption: IV, IM, nasal spray or jelly, ophthalmic soln.
Dist.:
Metab.:
Excretion, t½:
Toxicity/S.E.s: Overuse of nasal spray ® rebound congestion (may be worse than previous congestion).
Utility: Induces vasoconstriction (IV). Prevents hypotension (IM). Nasal decongestant. Mydriatic (DOC for non-ophthalmologists). Eye drops to “get the red out.”
Special Features: a agonists gen. used to treat hypotension/shock, arrhythmia, nasal decongestion. Also induce local vasoconstriction.