Name: Desflurane (Suprane)
Class: General Anesthetic (Halogenated Hydrocarbon)
Mechanism: Stabilizes membranes of excitable tissue ® inhibition of action potential (primarily pre-synaptic blockade of synaptic transmission).
Absorption: Inhaled. Low blood solubility®Rapid onset of effect (BGPC = 0.42). MAC = 6-7.
Dist.: Dissolves in blood. Organs w/high perfusion are most affected.
Metabolism.: Some liver Metabolism.
Excretion, t½:
Toxicity/S.E.s: Moderately irritating. Low level of cardiac depression. Depresses circulation. Low potential for arrhythmia.
Utility: Induces general anesthesia.
Special Features: Produces rapid induction/awakening. Non-flammable. Satisfact. analgesia, good relaxation.