Name: Dextromethorphan
Class: Opioid (Semi-synthetic) (OTC)
Mechanism: Agonist of opioid receptors ® depression of CNS cough center.
Absorption: Oral.
Metabolism.: Hepatic conjug. ® polar Metabolismolites.
Excretion, t½: Urine.
Toxicity/S.E.s:High doses ® hallucinations. Potentially fatal interactions with MAOIs.
Utility: Antitussant.
Special Features: Minimal addiction/abuse liability.