Name: Terfenadine (Seldane)
Class: H1-Histamine Antagonist
Mech.: Competitive inhib. of histamine and histamine receptor interaction.
Absorption: Oral
Dist.: No CNS
Metab.:
Excretion, t½:
Toxicity/S.E.s:
Utility: Treat allergic rxns (e.g., hay fever).
Special Features: No anticholinergic activity. Few/no CNS effects. Probably not as effective as older antihistamines. Fails to produce even moderate relief of symptoms in many patients.