Name: Carbachol
Class: Cholinomimetic Agent
Mech.: Stim. muscarinic and nicotinic receptors. Stim. release of ACh from nerve terminals.
Absorption: Eye drops
Dist.:
Metab.:
Excretion, t½:
Toxicity/S.E.s:
Utility: Topical eye applic. to treat glaucoma. For closed-angle glaucoma, stim. constriction of iris sphincter ® iris removed from entrance to trabecular space. For open-angle glaucoma, stim. sphincter and ciliary body contraction ® patency of trabecular network. Topical for cataract surgery.
Special Features: Use only when pilocarpine doesn’t work, due to unpleasant side effect of ACh release.