Name: Ethambutol (Myambutol)
Class: Antitubercular
Mech.: Tuberculostatic, mech. unknown, may involve inhib of mycolic acid synth.
Absorption: Well absorbed orally. Not affected by food.
Distribution:
Metab.:
Excretion, t½: Renal excretion (50% unchanged and 15% inactive metab. in 24 hr)
Toxicity/S.E.s: Few. Decreased visual acuity and ability to perceive color green (usually reversible). Gout.
Utility: Treat TB. Resistance develops is used alone. Usu. used with isoniazid.
Special Features: