Name: Troglitazone
Class: Anti-Diabetes Agent (Oral Hypoglycemic)
Mechanism: glucose utilization and reduces production by receptor response to insulin.
Absorption:
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s:
Utility: May help prevent development of NIDDM.
Special Features:
Etiketler: Anti-Diabetes Agent (Oral Hypoglycemic)
Name: Acarbose (Precose)
Class: Anti-Diabetes Agent (Oral Hypoglycemic)
Mechanism: Inhibits a-glucosidase ® ¯ conversion of carbohydrates to glucose in the small intestine ® ¯ absorption of glucose ® ¯ post-prandial glucose rise. Does not stimulate insulin release or action. \ No hypoglycemia.
Absorption: Oral ® poor absorption.
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: Flatulence, diarrhea, abdominal cramping.
Utility: Treat NIDDM. Possible adjunct to insulin for IDDM.
Special Features:
Etiketler: Anti-Diabetes Agent (Oral Hypoglycemic)