Pharmacology Mnemonics - Flash Cards

Name: Morning-After Pill (Ovral, The Pill, etc.)

Class: Oral Contraceptive (Estrogen/Progestin Combination)

Mechanism: Blocks nidation by producing an unfavorable endometrium.

Absorption:

Dist.:

Metabolism.:

Excretion, t½:

Toxicity/S.E.s: Breast fullness, depression, dizziness, edema, headache, n/v, cardiovascular disease (esp. in smokers over age 35). C/i in presence of cerebrovascular and thromboembolic disease,
estrogen-dependent neoplasms, liver disease, and migraine headache.

Utility: Post-coital contraceptive. Usu. ~99% effective if admin. w/in 72 hours.

Special Features:

Name: The Pill (Various)

Class: Oral Contraceptive (Estrogen/Progestin Combination)

Mechanism: Blocks ovulation, suppresses endometrial growth, produces changes in cervical mucus ® block of sperm penetration.

Absorption: Oral.

Dist.: Metabolism.: Excretion, t½:

Toxicity/S.E.s: Breakthrough bleeding, amenorrhea, water retention, headache, breast fullness, depression, dizziness, edema, headache, n/v, weight gain, acne, cardiovascular disease (esp. in smokers over age 35). Absolute C/Is—thromboembolic disorder, CVA, CAD, ¯ liver fxn, hepatic adenoma, estrogen-dependent cancer (e.g., breast, endometrium), pregnancy, undiagnosed vaginal bleeding, tobacco use over age 35. Relative C/Is—migraine headaches, hypertension, leiomyomata, diabetes mellitus or prev. gestational diabetes, elective surgery, seizures or anticonvulsant use, obstructive jaundice in pregnancy, sickle cell disease, gall bladder disease.

Utility: Contraception, dysmenorrhea, prophylaxis against endometriosis.

Special Features: Decreases the risks of endometrial and ovarian cancer and benign breast disease.