Pharmacology Mnemonics - Flash Cards

Name: Medroxyprogesterone (Depo-Provera)

Class: Long-Acting Contraceptive (Progestin-Only)

Mechanism: Doesn’t always inhibit ovulation. Produces changes in cervical mucus ® block of sperm penetration.

Absorption: IM

Dist.:

Metabolism.:

Excretion, t½:

Toxicity/S.E.s: Irregular menstrual bleeding, headaches, depression. Drug
cannot be removed to alleviate side effects.

Utility: Contraception, esp. in patients c/i for estrogen therapy.

Name: Levonorgestrel (Norplant)

Class: Long-Acting Contraceptive (Progestin-Only)

Mechanism: Doesn’t always inhibit ovulation. Produces changes in cervical mucus ® block of sperm penetration.

Absorption: Subcutaneous implant

Dist.:

Metabolism.:

Excretion, t½:

Toxicity/S.E.s: Irregular menstrual bleeding and headaches.

Utility: Contraception, esp. in patients c/i for estrogen therapy.

Special Features: Cheaper than oral contraceptives, completely reversible, and good for 5 years. Probably the most effective reversible method of contraception available. None of the cardiovascular toxicity of the combination pill.