Name: Tranexamic Acid (Amstat)
Class: Thrombolytic Agent Antagonist
Mechanism: Competitive inhib. of plasminogen activation.
Absorption: Oral.
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s:
Utility: Used for hemostasis in pts. undergoing oral surgery who are being treated w/oral anticoagulants.
Special Features:
Etiketler: Thrombolytic Agent Antagonist
Name: Aminocaproic Acid (Amicar)
Class: Thrombolytic Agent Antagonist
Mechanism: Lysine analog. Binds to lysine sites on plasminogen and plasmin ® blocks binding of plasmin to fibrin.
Absorption: IV (slow injxn).
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: Thrombi that form during treatment are not lysed. Thrombosis may become a problem.
Utility: Treat bleeding from fibrinolytic therapy.
Special Features:
Etiketler: Thrombolytic Agent Antagonist