Pharmacology Mnemonics - Flash Cards

Name: Ritodrine (Yutopar)

Class: b2 Agonist

Mech.: Selective b2 stim.

Absorption: IV

Dist.:

Metab.:

Excretion, t½:

Toxicity/S.E.s: Tachycardia, arrhythmia, MI. ­ risk w/underlying CV disease or use of MAO inhib. or tricyclics. Skeletal muscle tremor, restlessness, anxiety, apprehension. ¯ arterial O2 tension. High doses may cause myocard. necrosis, ¯ plasma K+, ­ plasma glucose. ­ hyperglycemia in diabetics, ¯ K+ in cardiac patients (esp. those taking cardiac glycosides and diuretics).

Utility: Uterine relaxant. Suppresses premature labor.

Special Features: Only drug approved in US to delay or prevent premature labor.

Name: Albuterol (Proventil, Ventolin)

Class: b2 Agonist

Mech.: More selective than terbutaline for b2 receptors.

Absorption: Aerosol inhalation ® bronchodilation w/in 15 min. Effects last 3-4 hr. Nebulized inhalation, oral.

Dist.:

Toxicity/S.E.s: Less likely w/inhalation. Tachycardia, arrhythmia, MI. ­ risk w/underlying CV disease or use of MAO inhib. or tricyclics. Skeletal muscle tremor, restlessness, anxiety, apprehension. ¯ arterial O2 tension. High doses may cause myocard. necrosis, ¯ plasma K+, ­ plasma glucose. ­ hyperglycemia in diabetics, ¯ K+ in cardiac patients (esp. those taking cardiac glycosides and diuretics).

Utility: Treat asthma.

Special Features: b2s are DOCs for sympathomimetic treatment of asthma. Metered inhaler approved for kids ³ 4 y.o.

Name: Terbutaline (Brethine)

Class: b2 Agonist

Mech.: Selectively stim. b2.

Absorption: Inhalation, oral, subcut.

Toxicity/S.E.s: Not recommended for kids < style=""> Tachycardia, arrhythmia, MI. ­ risk w/underlying CV disease or use of MAO inhib. or tricyclics. Skeletal muscle tremor, restlessness, anxiety, apprehension. ¯ arterial O2 tension. High doses may cause myocard. necrosis, ¯ plasma K+, ­ plasma glucose. ­ hyperglycemia in diabetics, ¯ K+ in cardiac patients (esp. those taking cardiac glycosides and diuretics).

Utility: Treat asthma. Suppress premature labor.

Special Features: Only b2 bronchodilator for parenteral use in emergency treatment of status asthmaticus. b2s are DOCs for sympathomimetic treatment of asthma.

Name: Metaproterenol (Alupent)

Class: b2 Agonist

Mech.: b2 selective, but not as much as albuterol or terbutaline.

Absorption: Oral ® 40%. Inhalation of aerosol (onset in minutes).

Dist.:

Metab.:

Excretion, t½: Effects last 3-4 hrs.

Toxicity/S.E.s: Less likely w/inhalation. Tachycardia, arrhythmia, MI. ­ risk w/underlying CV disease or use of MAO inhib. or tricyclics. Skeletal muscle tremor, restlessness, anxiety, apprehension. ¯ arterial O2 tension. High doses may cause myocard. necrosis, ¯ plasma K+, ­ plasma glucose. ­ hyperglycemia in diabetics, ¯ K+ in cardiac patients (esp. those taking cardiac glycosides and diuretics).

Utility: Treat asthma.

Special Features: b2s are DOCs for sympathomimetic treatment of asthma.