Name: Medroxyprogesterone (Depo-Provera)
Class: Long-Acting Contraceptive (Progestin-Only)
Mechanism: Doesn’t always inhibit ovulation. Produces changes in cervical mucus ® block of sperm penetration.
Absorption: IM
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: Irregular menstrual bleeding, headaches, depression. Drug
cannot be removed to alleviate side effects.
Utility: Contraception, esp. in patients c/i for estrogen therapy.
Special Features: None of the cardiovascular toxicity of the combination pill.