Name: Terbutaline (Brethine)
Class: b2 Agonist
Mech.: Selectively stim. b2.
Absorption: Inhalation, oral, subcut.
Toxicity/S.E.s: Not recommended for kids < style=""> Tachycardia, arrhythmia, MI. risk w/underlying CV disease or use of MAO inhib. or tricyclics. Skeletal muscle tremor, restlessness, anxiety, apprehension. ¯ arterial O2 tension. High doses may cause myocard. necrosis, ¯ plasma K+, plasma glucose. hyperglycemia in diabetics, ¯ K+ in cardiac patients (esp. those taking cardiac glycosides and diuretics).
Utility: Treat asthma. Suppress premature labor.
Special Features: Only b2 bronchodilator for parenteral use in emergency treatment of status asthmaticus. b2s are DOCs for sympathomimetic treatment of asthma.