Name: Calcium glubionate (Neo-Calglucon)
Class: Element
Mechanism:
Absorption: Oral usu. ® 15-20% (up to 50% w/maximal stimulation).
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: Hypercalcemia, hypercalciuria, diarrhea. Drug interactions—¯ bioavailability and/or oral absorption of some drugs (e.g., etidronate, tetracyclines, iron salts, atenolol, norfloxacin). Thiazide diuretic-induced hypercalcemias exacerbated by calcium supplementation.
Utility: Treat mild hypocalcemia. Also maintenance after initial IV treatment. Provide 400-800 mg/d. Reduces/prevents bone loss in older women (800 mg/d).
Special Features: 6.5% calcium. Probably obsolete due to large number of
tablets necessary to obtain effect.