Name: Iodide
Class: Antithyroid drug
Mechanism: High doses of iodide inhibit thyroid gland fxn. Effects decrease w/time, possible due to decrease in iodide transport.
Absorption:
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Excretion, t½:
Toxicity/S.E.s:
Utility: Used in conjunction w/thioamides for preoperative preparation to diminish vascularity and swelling of thyroid gland ® reduced operative mortality. Treatment of thyrotoxicosis. Blocks synthesis and release of thyroid hormones. Rapid effect.
Special Features: No longer used very much.