Name: Amrinone (Inocor)
Class: CHF Rx (PDE Inhibitor)
Mechanism: Inhib. of PDE III® cAMP ® contractility, stroke volume, ejection fraction, heart rate, exercise capacity. In smooth muscle, inhib. ® vasodilation.
Absorption: IV only.
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: mortality from heart failure (possibly due to arrhythmogenesis).
Utility: Treat CHF.
Special Features: