Name: Al-Mg Hydroxides
Class: Antacid
Mechanism: Weak base ® ¯ gastric acidity. pH ® ¯ peptic activity.
Absorption:
Dist.:
Metabolism.:
Excretion, t½:
Toxicity/S.E.s: Al3+ can form insoluble complexes w/other drugs ® ¯ absorption (e.g., tetracycline).
Utility: PUD
Special Features: Comb. of constipation (Al) and laxative (Mg) effects may cancel ® rel. normal bowel function.