Name: Benzocaine
Class: Local Anesthetic (Ester)
Mechanism: Blocks Na+ & Ca2+ channels ® ¯ rate of rise of action potential, failure to propagate action potential, eventual conduction block. Smaller, unmyelinated fibers are more easily blocked and remain blocked longer.
Absorption: Topical use only.
Dist.:
Metabolism.: Absorbed benzocaine is rapidly Metabolism. by plasma pseudocholinesterases.
Excretion, t½:
Toxicity/S.E.s: Too slowly absorbed to produce serious systemic toxicity..
Utility: Sustained anesthetic effect when applied to wounds and ulcerated surfaces.
Special Features: