Name: Halothane (Fluothane)
Class: General Anesthetic (Halogenated Hydrocarbon)
Mechanism: Stabilizes membranes of excitable tissue ® inhibition of action potential (primarily pre-synaptic blockade of synaptic transmission).
Absorption: Inhaled. High blood solubility®Rel. slow onset of effect (BGPC = 2.3). MAC = 0.77.
Dist.: Dissolves in blood. Organs w/high perfusion are most affected.
Metabolism.: Some liver Metabolism.
Excretion, t½:
Toxicity/S.E.s: High level of cardiac depression. Depresses circulation. May produce fatal hepatitis. Med. high potential for arrhythmia. Avoid repeated exposure.
Utility: Induces general anesthesia.
Special Features: Non-irritating, non-flammable. Satisfact. analgesia and muscle relaxation.