Name: Trimethaphan (Arfonad)
Class: Ganglionic Blocking Agent
Mech.: Blocks nerve transmission at parasympathetic and sympathetic ganglia. Direct peripheral vasodilation. Non-selective.
Absorption: Only IV admin.
Dist.:
Metab.:
Excretion, t½: Short duration of action.
Toxicity/S.E.s: Hypotension—requires constant monitoring of blood pressure during administration.
Utility: Treat hypertensive emergencies. Produce controlled hypotension during surgery.
Special Features: