Name: Ipratropium (Atrovent)
Class: Quaternary M2-Muscarinic Antagonist
Mech.: Bind to muscarinic receptors and competitively inhib. ACh interaction.
Absorption: Inhalation ® local effect (minimal systemic absorption)
Dist.:
Metab.:
Excretion, t½:
Toxicity/S.E.s:
Utility: Produces bronchodilation. Treat bronchospasm assoc. w/asthma and COPD (including chronic bronchitis and emphysema).
Special Features: Effect prolonged when combined w/a b2-adrenergic agonist.