Name: Pralidoxime (Protopam)
Class: Cholinesterase Reactivator
Mech.: Hydrolyzes phosphorylated AChE, provided the complex has not “aged.”
Absorption:
Dist.: No CNS.
Metab.:
Excretion, t½:
Toxicity/S.E.s:
Utility: Counteracts NM activation and paralysis due to organophosphorous poisoning. Must be given ASAP.
Special Features: