Name: Nystatin
Class: Antifungal (Polyene)
Mech.: Assoc. w/ergosterol in fungal membrane ® 4-5 Å pores. Fungistatic at low conc. Fungicidal at high conc.
Absorption: Poor oral absorption. Topical admin.
Distribution:
Metab.:
Excretion, t½:
Toxicity/S.E.s: No side effects when topically applied
Utility: Superficial candidiasis (GI, cutaneous, oropharyngeal, vulvovaginal) via topical, oral, or vaginal admin.
Special Features: Safe during pregnancy.