Name: Probenecid
Class:
Mech.: Interferes w/renal excretion of drugs that undergo tubular secretion. Inhib. glucuronide conjugation of other drugs.
Absorption:
Distribution:
Metab.:
Excretion, t½:
Toxicity/S.E.s:
Utility:
Special Features: Decreases renal excretion of methotrexate — possible toxicity. Decreases renal excretion of penicillin.